Dr. Rossana Arroyo Verástegui
Cinvestav Researcher 3D. Doctor in Sciences (1987). Cinvestav.
SNI: Level 2

rarroyo@cinvestav.mx

• Our group research interests are: 1) Molecular pathogenesis of trichomoniasis, particularly cytoadherence, cytotoxicity/apoptosis and hemolysis events. This has allowed us to identify and characterize some cysteine proteinase (CPs), endogenous CPs inhibitors (tricocystatins), aspartic proteases and multifunctional proteins such as adhesins and receptors for extracellular matrix (metabolic enzymes) as virulence factors of Trichomonas vaginalis. 2) Participation of environmental factors such as iron and glucose in gene expression regulation. We have identified an atypical iron-mediated post-transcriptional regulation mechanism involving atypical RNA-binding proteins as multifunctional cytoskeleton and heat shock proteins. 3) Unconventional transport pathways for vesicles by autophagy of the hydrogenosome (hydrogenophagy), as part of the mechanisms of relocation of multifunctional proteins to the parasite membrane. 4) Recombinant virulence factors as potential targets for diagnosis. 5) Search for therapeutic and vaccine targets for T. vaginalis infection.

Dr. Bibiana Chávez Munguía
Researcher Cinvestav 3A.  Doctor in Sciences (1995) Cinvestav.
SNI: Level 2

bchavez@cinvestav.mx

• Research topics: Cell biology of Giardia lamblia, Entamoeba histolytica, dispar and invadens. Study of the cytopathic effect produced by these parasites in vitro. Relationship of different species of the genus Plasmodium and Anopheles vectors. Ultrastructural features of mosquitoes from the genus Anopheles.  Ultrastructure of intercellular junctions.

Dr. Rosa María del Ángel Núñez de Cáceres
Researcher Cinvestav 3D. Doctor in Sciences (1990). Cinvestav.
SNI: Level 3

rmangel@cinvestav.mx

• Research topics: Our group is actually involved in the analysis of cellular mechanisms and components used by Flaviviridae family members such as Dengue, Zika and Yellow Fever virus to enter, replicate, inhibit the cellular immune response and exit the host cell. This study has allowed us to find cellular factors that favor and others that avoid viral multiplication in infected cells.
  
  With this information we have identified molecules and components that are capable to block viral infection and we are testing their usefulness as antivirals in cell culture systems and in animal models.
  
  On the other hand, we work on the identification of cellular communication mechanisms such as exosomes in mosquito cells and their participation in Dengue virus pathogenesis.

Dr. Martha Espinosa
Researcher Cinvestav 3B. Doctor in Sciences (1994). Cinvestav.
SNI: Level 1

mespinos@cinvestav.mx

• Research topics: Characterization of Entamoeba dispar, cell biology of E. histolytica and E. dispar, in vivo pathogenesis of Entamoeba dispar, role of Trichomonas vaginalis in HIV transmission.

Dr. Ana Lorena Gutiérrez Escolano
Researcher Cinvestav 3C. Doctor inSciences (1997). Cinvestav.
SNI: Level1

alonso@cinvestav.mx

• Research topics: Calicivirus.replication. Molecular characterization of Norwalk virus, a causative agent of gastroenteritis in humans. Some aspects of the epidemiology in México.  Host-cell interactions of feline calicivirus and murine norovirus. Role of cellular proteins in viral replication.

Dr. Arturo González Robles
Researcher Cinvestav 3A. Doctor in Science (1995). Cinvestav.
SNI: Level 2

goroa@cinvestav.mx

• Research topics: ultrastructural characterization and description of some biological processes of free-living amoebae. Mechanisms of pathogenicity on cell cultures and hamster cornea.

Dr. Fidel de la Cruz Hernández Hernández

Researcher Cinvestav 3C. Doctor in Science (1990). Cinvestav.
SNI: Level 2

cruzcruz@cinvestav.mx
cruzcruz@correo.insp.mx

• Research interests: Molecular biology of blood-sucking insects that transmit parasitic diseases: anophelines and triatomines. Regulators of Plasmodium cell  cycle. Molecular biology of Staphylococcus aureus.

Dr. Juan Bautista Kouri Flores
Researcher Cinvestav 3D. Doctor inScience (1973). National Center for Scientific Research. University of Havana, Cuba.
SNI: Level 2

bkouri@cinvestav.mx

• Research topics: Etiopathogenesis of osteoarthritis. Characterization of the degenerative processes and cell death in articular cartilage degradation, being the pioneer in describing the apoptosis in this process.

Dr. Juan E. Ludert
Researcher Cinvestav 3C. Doctor in Microbiology (1996). Venezuelan Institute for Scientific Research (IVIC).
SNI: Level 2

jludert@cinvestav.mx

• Research topics: Pathogenesis of the disease caused by dengue virus. Identification of resistance factors and host susceptibility to the infection.

Dr. Adolfo Martínez Palomo
Emeritus Researcher. Doctor in Medical Sciences (1971). UNAM.
SNI: National Researcher Emeritus

amartine@cinvestav.mx

• Research topics: biology of the cancer cell. Biology, pathology and control of infections caused by protozoan pathogens. Structure and function of the tight junctions in epithelia. Promotion of molecular parasitology and health research.

Dr. Maria Esther Orozco Orozco
Emeritus Researcher.  Professor Cinvestav 3F. Doctor of Sciences (1981). Cinvestav.
SNI: Level 3 National Researcher Emeritus

esther@cinvestav.mx

I)   Study of the proteins involved in the virulence of Entamoeba histolytica.
II)  Search and analysis of the elements of the ESCRT machinery in Entamoeba histolytica.
III) Search for SUMO protein and SUMOylation machinery in Entamoeba histolytica.
IV) Characterization of the SUMOylation process in phagocytosis and other virulence functions.
V)  Study of the secretion of EhADH and other proteins and their importance in the virulence of amoeba.

Dr. Mario Alberto Rodríguez-Rodríguez
Researcher Cinvestav 3C. Doctor in Science (1990). Cinvestav.
SNI: Level 2

marodri@cinvestav.mx

• Research topics: Isolation and characterization of molecules involved in the host-parasite relationship of Entamoeba histolytica.

Dr. José Luis Rosales Encina
Researcher Cinvestav 3D. Doctor in Science (1987). Cinvestav.
SNI: Level 2

rosales@cinvestav.mx

• Research topics: Molecular biology, biochemistry and immunology of Entamoeba histolytica, Trypanosoma cruzi and Leishmania mexicana.

Dr. Matilde Mineko Shibayama Salas
Researcher Cinvestav 3C. Doctor in Science (1998). Cinvestav.
Academic Coordinator
SNI: Level 3

mineko@cinvestav.mx

• Research Topics: Characterization of in vivo experimental models for the study of amebiasis by Entamoeba histolytica, immunopathology, cell biology, and ultrastructure of E. histolytica and the free-living amebas, Naegleria fowleri, and Acanthamoeba spp. Liver cirrhosis and hapatocellular cancer.

Dr. Patricia Talamás Rohana
Researcher Cinvestav 3D. Doctor in Science (1987). Cinvestav.
SNI: Level 2

ptr@cinvestav.mx

• Research Topics: Cell Biology and Immunology of protozoan parasites.

Dr. Víctor Katsutoshi Tsutsumi Fujiyoshi
Researcher Cinvestav 3D. Doctor in Science (1992). IPN.
SNI: Level 3.

vtsutsu@cinvestav.mx

• Research topics: Characterization of experimental models for the study of protozoan parasitic infections (amebiasis, malaria, trichomoniasis, free-living amebas). Hepatic ultrastructure and immunopathology, Liver cirrhosis and hepatocellular cancer.

Dr. Marco Antonio Vega Lopez
Researcher Cinvestav 3A. Doctor in Science in Immunology (Ph.D., 1991)
University of Bristol, UK.
SNI: Level I

mavega@cinvestav.mx

• Research topics: Mucosal Immunobiology. Structure and development of the mucosal immune system, in the respiratory and intestinal tracts and in the skin of laboratory animal models and domestic animals (pigs). Effect of infections in the mucosal immune system. Development of mucosal and perinatal immunization protocols. Immune stimulation.